Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 2/20 | 0.46 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470242 | 0.88 | TRPC3 (0.51) | TRPC3TRPC7KCNK3KCNK9SMN1; SMN2 | |
| SCHEMBL4835253 | 0.78 | TRPC3 (0.49) | TRPC3TRPC7 | |
| SCHEMBL4836747 | 0.77 | TRPC3 (0.47) | TRPC3TRPC7GRIN2B | |
| SCHEMBL4906701 | 0.77 | TRPC3 (0.47) | TRPC3TRPC7 | |
| SCHEMBL4468918 | 0.77 | MAPK14 (0.52) | — | |
| SCHEMBL4893233 | 0.76 | TRPC3 (0.47) | TRPC3TRPC7 | |
| SCHEMBL4458503 | 0.75 | TRPC3 (0.53) | TRPC3TRPC7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18031475 | 0.69 | TRPC3 (0.55) | TRPC3TRPC7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18031474 | 0.67 | TRPC3 (0.53) | TRPC3TRPC7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4035554 | 0.66 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9APDE4BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429590-B2 | Antiprotozoal imidazopyridine compounds | MERCK & CO. INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429590-B2 | Antiprotozoal imidazopyridine compounds | MERCK & CO. INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429590-B2 | Antiprotozoal imidazopyridine compounds | MERCK & CO. INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-20060293303-A1 | Antiprotozoal imidazopyridine compounds | MERCK SHARP & DOHME LLC | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293303-A1 | Antiprotozoal imidazopyridine compounds | PNPO, PIR, PNP | TRPC3 4659/4885TRPC7 4549/4885KCNK3 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.