Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 1/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | XDH | P47989 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461855 | 0.83 | CENPE (0.61) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL13161979 | 0.83 | CENPE (0.61) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL14531634 | 0.81 | CENPE (0.64) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL2617273 | 0.81 | CENPE (0.64) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL3461448 | 0.81 | CENPE (0.65) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL13161815 | 0.81 | CENPE (0.65) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL3461841 | 0.80 | CENPE (0.70) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL13162058 | 0.80 | CENPE (0.64) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL13161539 | 0.80 | CENPE (0.70) | CENPES1PR1S1PR5S1PR3XDH | |
| SCHEMBL3462485 | 0.80 | CENPE (0.64) | CENPES1PR1S1PR5S1PR3XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742907-A4 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1742907-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005107762-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2005-11-17 | — | — | WO | disclosed |