SCHEMBL483884

SCHEMBL483884

NCC(=O)NCC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 4/20 0.39
GRIK2 Q13002 2/20 0.39
GRM1 Q13255 1/20 0.39
GRM2 Q14416 1/20 0.39
SLC7A5 Q01650 1/20 0.38
MMP2 P08253 1/20 0.37
SLC1A1 P43005 2/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
GGT1 P19440 2/20 0.35
GSR P00390 1/20 0.35
GRIA4 P48058 1/20 0.35
GRIK3 Q13003 1/20 0.35
GRIK5 Q16478 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8017465 0.87 SLC7A5 (0.43) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL8346463 0.80 PTGS1 (0.41) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL3044802 0.77 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL3145928 0.77 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL564563 0.77 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
Leucine SCHEMBL9419205 0.75 SLC7A5 (0.60) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
Cysteine SCHEMBL28235428 0.74 PTGS1 (0.57) GRIK1GRIK2GRM1GRM2MMP2
SCHEMBL2807629 0.74 PTGS1 (0.45) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL2807626 0.74 PTGS1 (0.45) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL1768374 0.72 OTC (0.50) GRIK1GRIK2GRM1GRM2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120034276-A1 SOLID PREPARATION ASKA PHARMACEUTICAL CO., LTD. 2012-02-09 US disclosed
EP-2412366-A1 SOLID PREPARATION LINTEC Corporation (JP) 2012-02-01 EP disclosed
EP-1375521-B1 CELLULOSE ACYLATE AND SOLUTION THEREOF FUJIFILM CORP (JP) 2011-10-12 EP disclosed
EP-1422244-B1 Film comprising a cellulose triacetate and method of producing the same DAICEL CHEM (JP) 2009-08-19 EP disclosed
EP-0943626-B1 Cellulose acetate and dope containing the same DAICEL CHEM (JP) 2006-12-13 EP disclosed
US-7148344-B2 Method for producing cellulose acetate film DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-12-12 US disclosed
US-7122660-B1 Cellulose acetate and dope containing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-10-17 US disclosed
US-6984730-B2 Cellulose acylate and solution thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-01-10 US disclosed
US-20050187385-A1 Cellulose acetate and dope containing the same DAICEL CHEMICAL INDUSTRIES, LTD. 2005-08-25 US disclosed
US-6914139-B2 Solution of cellulose acylate dissolved in mixed solvent of ketone and ester FUJI PHOTO FILM CO., LTD. (JP) 2005-07-05 US disclosed
EP-1422244-A1 Film comprising a cellulose triacetate and method of producing the same Daicel Chemical Industries, Ltd. (JP) 2004-05-26 EP disclosed
US-20040059106-A1 Cellulose acylate and solution thereof FUJIFILM CORPORATION (JP) 2004-03-25 US disclosed
EP-1375521-A1 CELLULOSE ACYLATE AND SOLUTION THEREOF FUJI PHOTO FILM CO., LTD. (JP) 2004-01-02 EP disclosed
US-20030164115-A1 Solution of cellulose acylate dissolved in mixed solvent comprising ketone and ester FUJIFILM CORPORATION (JP) 2003-09-04 US disclosed
EP-1333055-A1 SOLUTION OF CELLULOSE ACYLATE IN MIXED SOLVENT COMPRISING KETONE AND ESTER Fuji Photo Film Co., Ltd. (JP) 2003-08-06 EP disclosed
EP-0882768-B1 Method for producing of phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2001-12-19 EP disclosed
WO-2000068695-A2 REAGENT AND PROCESS FOR PEPTIDE/PROTEIN DIFFERENTIATION USING CIRCULAR DICHROISM DETECTION UNIV OKLAHOMA STATE (US) 2000-11-16 WO disclosed
US-6034236-A REACTING A PHTHALONITRILE WITH A METAL OXIDE IN PRESENCE OF A SULFONIC ACID CATALYST NIPPON SHOKUBAI CO., LTD. (JP) 2000-03-07 US disclosed
EP-0943626-A1 Cellulose acetate and dope containing the same Daicel Chemical Industries, Ltd. (JP) 1999-09-22 EP disclosed
EP-0882768-A2 Method for producing of phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-09 EP disclosed