Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 4/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564563 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL3044802 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL2474141 | 0.83 | SLC7A5 (0.54) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL29148903 | 0.83 | SLC7A5 (0.54) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL10618897 | 0.81 | PTGS1 (0.55) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL6832737 | 0.81 | PTGS1 (0.55) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL5296510 | 0.80 | GRIK1 (0.46) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL6831240 | 0.80 | GRIK1 (0.46) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Aspartic Acid SCHEMBL7717425 | 0.79 | GLRA1 (0.53) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Aspartic Acid SCHEMBL307008 | 0.79 | GLRA1 (0.53) | GRIK1GRIK2GRM1GRM2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925771-B1 | A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES | COUNCIL SCIENT IND RES (IN) | 2021-08-18 | — | — | EP | claimed |
| WO-2023034929-A1 | ENZYME AND RELATIVE HUMIDITY RESPONSIVE ANTIMICROBIAL FIBERS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-03-09 | — | — | WO | disclosed |
| EP-2925771-B1 | A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES | COUNCIL SCIENT IND RES (IN) | 2021-08-18 | — | — | EP | disclosed |
| US-7705050-B2 | Amides, useful in the inhibition of IL-8-induced chemotaxis of neutrophils | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2010-04-27 | — | — | US | disclosed |
| EP-1255726-B1 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS | DOMPE PHA R MA SPA RES & MFG (IT) | 2009-11-11 | — | — | EP | disclosed |
| US-20040181073-A1 | Amides, useful in the inhibition of il-8-induced chemotaxis of neutrophils | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2004-09-16 | — | — | US | disclosed |
| US-20040127506-A1 | Antimycobacterial compounds | YATVIN MILTON B (US) | 2004-07-01 | — | — | US | disclosed |
| US-6664257-B2 | Such as derivatives of n-butyl-pyrazinamide for treatment of tuberculosis | ENZREL INC. | 2003-12-16 | — | — | US | disclosed |
| US-20030100569-A1 | Anti-mycobacterial compounds | ENZREL INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003039457-A2 | ANTI-MYCOBACTERIAL COMPOUNDS | ENZREL, INC (US) | 2003-05-15 | — | — | WO | disclosed |
| US-5534497-A | RADIOPHARMACEUTICALS; MEDICAL DIAGNOSIS | MALLINCKRODT MEDICAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5187264-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT MEDICAL, INC. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0250013-B1 | TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4849511-A | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0250013-A1 | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1987-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181073-A1 | Amides, useful in the inhibition of il-8-induced chemotaxis of neutrophils | CXCL8, MMP8, CCR8 | GRIK1 2769/4885GRIK2 2775/4885GRM1 3066/4885 |
| US-20040127506-A1 | Antimycobacterial compounds | IMMT, MT-ND5, ACAT1 | GRIK1 4640/4885GRIK2 4682/4885GRM1 4318/4885 |
| US-20030100569-A1 | Anti-mycobacterial compounds | IMMT, PML, TBC1D5 | GRIK1 4703/4885GRIK2 4706/4885GRM1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.