SCHEMBL483885

SCHEMBL483885

c1ccc(-c2cccc3sc4ccccc4c23)nc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.49
GABRA1 P14867 1/20 0.49
KDM4E B2RXH2 8/20 0.44
NPC1 O15118 5/20 0.44
RAB9A P51151 4/20 0.44
MAPT P10636 3/20 0.44
GLA P06280 1/20 0.44
TP53 P04637 5/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 1/20 0.44
TGFBR1 P36897 2/20 0.43
LMNA P02545 3/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31614324 1.00 MIF (0.49) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL28725157 0.88 MIF (0.51) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL31526880 0.84 KDM4E (0.46) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL21300596 0.84 KDM4E (0.37) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL21295907 0.81 MIF (0.44) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL23098922 0.81 KRAS (0.39) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL16838922 0.80 MIF (0.49) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL30302872 0.80 MIF (0.44) MIFGABRA1KDM4ENPC1RAB9A
SCHEMBL16553298 0.80 GPR3 (0.59) KDM4ENPC1RAB9AMAPTSMN1; SMN2
SCHEMBL30550557 0.80 GPR3 (0.59) KDM4ENPC1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041376-B Ring metal iridium complex and preparation method and application thereof 江西师范大学 2021-10-29 CN claimed
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 EP disclosed
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-05-30 US disclosed
US-11910701-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 US disclosed
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
CN-112028941-B Heteroleptic iridium complexes 通用显示公司 2023-08-29 CN disclosed
US-11637251-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-04-25 US disclosed
CN-113121603-B Phosphorescent iridium complex serving as OLED (organic light emitting diode) doping material and application thereof 江苏三月科技股份有限公司 2023-02-24 CN disclosed
US-20140203268-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2014-07-24 US disclosed
US-8722205-B2 Heteroleptic iridium complex UNIVERSAL DISPLAY CORPORATION (US) 2014-05-13 US disclosed
EP-2710020-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY Universal Display Corporation (US) 2014-03-26 EP disclosed
EP-2650941-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2013-10-16 EP disclosed
US-20130248845-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-09-26 US disclosed
WO-2012158851-A1 PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY UNIVERSAL DISPLAY CORPORATION (US) 2012-11-22 WO disclosed
CN-102439019-A Heteroleptic iridium complexes UNIVERSAL DISPLAY CORP 2012-05-02 CN disclosed
EP-2411401-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2012-02-01 EP disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11910701-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 MIF 2243/4885GABRA1 1335/4885KDM4E 2475/4885
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 MIF 2243/4885GABRA1 1335/4885KDM4E 2475/4885
US-11637251-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 MIF 2243/4885GABRA1 1335/4885KDM4E 2475/4885
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 MIF 2243/4885GABRA1 1335/4885KDM4E 2475/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 MIF 3224/4885GABRA1 292/4885KDM4E 3232/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 MIF 1375/4885GABRA1 2372/4885KDM4E 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.