Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850075 | 0.88 | CCR2 (0.53) | CCR2RXFP1 | |
| SCHEMBL4841072 | 0.84 | CCR2 (0.38) | CCR2RXFP1 | |
| SCHEMBL4839187 | 0.83 | CCR2 (0.46) | CCR2RXFP1HTR2CEPHX1 | |
| SCHEMBL4839283 | 0.81 | CCR2 (0.49) | CCR2RXFP1HTR2CEPHX1IGF2BP2 | |
| SCHEMBL5449234 | 0.81 | CCR2 (0.49) | CCR2RXFP1HTR2CEPHX1IGF2BP2 | |
| SCHEMBL2991053 | 0.79 | IGF2BP2 (0.46) | CCR2RXFP1IGF2BP2KCNK2KCNK10 | |
| SCHEMBL5436646 | 0.79 | CCR2 (0.44) | CCR2RXFP1IGF2BP2KCNK2KCNK10 | |
| SCHEMBL27529465 | 0.76 | CCR2 (0.42) | CCR2IGF2BP2 | |
| SCHEMBL27529466 | 0.76 | CCR2 (0.42) | CCR2IGF2BP2 | |
| SCHEMBL7384811 | 0.73 | MAPK14 (0.51) | CCR2RXFP1HTR2CIGF2BP2KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| CN-1240699-C | Therapeutic or prophylactic agent for chemokine-associated diseases | TEIJIN LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |