Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 6/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.49 |
| ▸ | PARP3 | Q9Y6F1 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844426 | 0.94 | PARP1 (0.56) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL4850567 | 0.93 | PARP1 (0.57) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL4841013 | 0.91 | PARP1 (0.58) | KMT2AKDM4EALDH1A1PARP1PARP2 | |
| SCHEMBL4848459 | 0.91 | GRM2 (0.50) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL4847358 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1GAAPARP1POLB | |
| SCHEMBL4840236 | 0.76 | CYP2D6 (0.46) | KMT2AMEN1ALDH1A1MC4RMC5R | |
| SCHEMBL4846986 | 0.75 | PARP1 (0.53) | KDM4EALDH1A1GAAPARP1PARP2 | |
| SCHEMBL4848291 | 0.75 | PARP1 (0.52) | KDM4EALDH1A1GAAPARP1PARP2 | |
| SCHEMBL4846900 | 0.75 | CYP2D6 (0.48) | KMT2AMEN1ALDH1A1MC4RMC5R | |
| SCHEMBL4839412 | 0.75 | KMT2A (0.51) | KMT2AMEN1MC4RMC5RPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368462-B1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| US-20080058423-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058423-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC4R | KMT2A 2587/4885MEN1 330/4885KDM4E 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.