Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.58 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.58 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839401 | 0.91 | KMT2A (0.51) | PARP1PARP2PARP3KDM4EALDH1A1 | |
| SCHEMBL4844426 | 0.88 | PARP1 (0.56) | PARP1PARP2PARP3CHEK1KDM4E | |
| SCHEMBL4850567 | 0.87 | PARP1 (0.57) | PARP1PARP2PARP3CHEK1SMN1; SMN2 | |
| SCHEMBL4848459 | 0.85 | GRM2 (0.50) | PARP1PARP2PARP3GRM2KDM4E | |
| SCHEMBL4841024 | 0.78 | NCF1 (0.61) | PARP1NCF1NOS1SMN1; SMN2KDM4E | |
| SCHEMBL3590235 | 0.78 | PARP1 (0.49) | PARP1PARP2PARP3GRM2NCF1 | |
| SCHEMBL145235 | 0.78 | PARP1 (0.49) | PARP1PARP2PARP3GRM2NCF1 | |
| SCHEMBL3641139 | 0.76 | PARP1 (0.51) | PARP1PARP2PARP3GRM2NCF1 | |
| SCHEMBL13162039 | 0.76 | CHUK (0.53) | PARP1PARP2PARP3NCF1NOS1 | |
| Hydrochloric Acid SCHEMBL347360 | 0.76 | PARP1 (0.48) | PARP1PARP2PARP3GRM2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368462-B1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-06 | — | — | US | disclosed |
| US-20080058423-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058423-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC4R | PARP1 4873/4885PARP2 4863/4885PARP3 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.