⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165719 | 0.82 | — | — | |
| SCHEMBL1828552 | 0.81 | — | — | |
| SCHEMBL104509 | 0.78 | — | — | |
| SCHEMBL105406 | 0.74 | KDM4E (0.32) | — | |
| SCHEMBL3577696 | 0.71 | MEN1 (0.32) | — | |
| SCHEMBL145412 | 0.71 | PNMT (0.52) | — | |
| SCHEMBL3531890 | 0.69 | — | — | |
| SCHEMBL4078314 | 0.69 | MEN1 (0.35) | — | |
| SCHEMBL11198759 | 0.68 | PDE3B (0.36) | — | |
| SCHEMBL130192 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912644-A2 | N-(ARYLALKYL)-1H-PYRROLOPYRIDINE-2-CARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF | Sanofi-Aventis (FR) | 2008-04-23 | — | — | EP | claimed |
| WO-2007010138-A2 | N(ARYLALKYL)-1H-PYRROLOPYRIDINE-2-CARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-01-25 | — | — | WO | claimed |