Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.57 |
| ▸ | PDE4A | P27815 | 11/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600073 | 0.89 | PDE4A (0.47) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1553512 | 0.82 | PDE4A (0.66) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8602395 | 0.81 | PDE4A (0.64) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604908 | 0.79 | SLC22A12 (0.67) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599922 | 0.79 | SLC22A12 (0.74) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8604859 | 0.78 | SLC22A12 (0.65) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8604636 | 0.78 | SLC22A12 (0.65) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8598410 | 0.78 | SLC22A12 (0.72) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8601162 | 0.77 | SLC22A12 (0.64) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1553375 | 0.77 | PDE4A (0.67) | SLC22A12PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329675-B2 | Substituted azabicyclic compounds | AVENTIS PHARMA LIMITED (GB) | 2008-02-12 | — | — | US | disclosed |
| US-20050038069-A1 | Substituted azabicyclic compounds | AVENTIS PHARMA LIMITED (GB) | 2005-02-17 | — | — | US | disclosed |
| US-6303600-B1 | USED IN THERAPY OF DISEASE STATES ASSOCIATED WITH PROTEINS THAT MEDIATE CELLULAR ACTIVITY | RHONE-POULENC RORER LIMITED (GB) | 2001-10-16 | — | — | US | disclosed |
| EP-0934307-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997048697-A1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | RHONE-POULENC RORER LIMITED (GB) | 1997-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038069-A1 | Substituted azabicyclic compounds | NR2C2, NR3C1, NR3C2 | SLC22A12 1326/4885PDE4A 3861/4885PDE4B 3722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.