SCHEMBL4840036

SCHEMBL4840036

CN(NS(C)(=O)=O)S(C)(=O)=O

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6750227 0.73
SCHEMBL28351607 0.71 CA2 (0.37) CA2
SCHEMBL5023754 0.67 CA2 (0.33) CA2
SCHEMBL11152784 0.65
SCHEMBL14566613 0.65
SCHEMBL48217 0.63
SCHEMBL9113181 0.63 CA2 (0.36) CA2
SCHEMBL28210389 0.62 CA2 (0.35) CA2
SCHEMBL875900 0.60 KDM4E (0.42) CA2
Trimethylammonium SCHEMBL700368 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074802-A It is used as the aryl triazoles yl pyridines of pesticide 拜耳动物保健有限责任公司 2017-08-18 CN claimed
US-7442704-B2 Amide derivatives ASTRAZENECA AB (SE) 2008-10-28 US claimed
CN-107074802-A It is used as the aryl triazoles yl pyridines of pesticide 拜耳动物保健有限责任公司 2017-08-18 CN disclosed
EP-1028721-B1 N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS UNIV YALE (US) 2003-06-04 EP disclosed
EP-0841912-B1 ANTITUMOR 2-AMINOCARBONYL-1,2-BIS(METHYLSULFONYL)-1-(SUBSTITUTED)HYDRAZINES UNIV YALE (US) 2002-09-25 EP disclosed
EP-1028721-A4 N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS UNIV YALE (US) 2001-01-31 EP disclosed
EP-1028721-A1 $i(N,N')-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS Yale University (US) 2000-08-23 EP disclosed
US-6040338-A N,n-bis(sulfonyl)hydrazines useful as antineoplastic agents YALE UNIVERSITY (US) 2000-03-21 US disclosed
WO-1999022726-A1 N,N'-BIS(SULFONYL)HYDRAZINES USEFUL AS ANTINEOPLASTIC AGENTS YALE UNIVERSITY (US) 1999-05-14 WO disclosed
EP-0841912-A4 ANTITUMOR 2-AMINOCARBONYL-1,2-BIS(METHYLSULFONYL)-1-(SUBSTITUTED)HYDRAZINES UNIV YALE (US) 1998-10-14 EP disclosed
EP-0841912-A1 ANTITUMOR 2-AMINOCARBONYL-1,2-BIS(METHYLSULFONYL)-1-(SUBSTITUTED)HYDRAZINES YALE UNIVERSITY (US) 1998-05-20 EP disclosed
US-5637619-A Antitumor 2-aminocarbonyl-1, 2-bis(methylsulfonyl)-1-(substituted)hydrazines YALE UNIVERSITY (US) 1997-06-10 US disclosed
WO-1997002029-A1 ANTITUMOR 2-AMINOCARBONYL-1,2-BIS(METHYLSULFONYL)-1-(SUBSTITUTED)HYDRAZINES YALE UNIVERSITY (US) 1997-01-23 WO disclosed
EP-0416286-B1 Sulfonylhydrazines and their use as antineoplastic agents and as antitrypanosomal agents UNIV YALE (US) 1995-08-09 EP disclosed
US-5214068-A Anticarcinogenic agents YALE UNIVERSITY (US) 1993-05-25 US disclosed
US-5101072-A Anticancer agents, trypanocides YALE UNIVERSITY (US) 1992-03-31 US disclosed
EP-0416286-A1 Sulfonylhydrazines and their use as antineoplastic agents and as antitrypanosomal agents YALE UNIVERSITY (US) 1991-03-13 EP disclosed