Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838626 | 0.84 | MAPT (0.36) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL28447576 | 0.82 | MAPT (0.35) | MAPTRAB9AAPPMEN1KMT2A | |
| SCHEMBL855273 | 0.82 | KCNH2 (0.38) | APPKCNH2 | |
| SCHEMBL2319369 | 0.80 | APP (0.34) | MAPTRAB9AMAOAMAOBAPP | |
| SCHEMBL10887757 | 0.79 | GRIA4 (0.34) | MAPTRAB9ALMNAPKMKCNH2 | |
| Hydrochloric Acid SCHEMBL10887735 | 0.76 | GRIA4 (0.33) | RAB9ALMNAPKMKCNH2ALDH1A1 | |
| SCHEMBL4931495 | 0.76 | MAPT (0.44) | MAPTRAB9AMEN1KMT2APOLB | |
| SCHEMBL3860929 | 0.75 | MAPT (0.41) | MAPTRAB9AMAOAMAOBAPP | |
| SCHEMBL7030236 | 0.75 | MAPT (0.41) | MAPTRAB9AMAOAMAOBAPP | |
| SCHEMBL15609308 | 0.74 | MAPT (0.38) | MAPTRAB9AAPPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047376-B1 | KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME | OREAL (FR) | 2001-05-23 | — | — | EP | claimed |
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| EP-0424261-A1 | Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent | L'OREAL (FR) | 1991-04-24 | — | — | EP | claimed |
| US-20130042882-A1 | COLORANTS FOR KERATINIC FIBRES HAVING OPTIMIZED VISCOSITY ADJUSTMENT | HENKEL AG & CO. KGAA (DE) | 2013-02-21 | — | — | US | disclosed |
| EP-2010494-B1 | SPECIFIC MONOCATIONIC MONOCHROMOPHORIC COMPOUNDS OF HYDRAZONE TYPE COMPRISING A 2-, 4-PYRIDINIUM OR 2-, 4-QUINOLINIUM UNIT, SYNTHESIS THEREOF, DYE COMPOSITIONS CONTAINING THEM, AND METHOD FOR DYEING KERATIN FIBRES | OREAL (FR) | 2012-02-01 | — | — | EP | disclosed |
| US-6383231-B1 | MIXTURE CONTAINING ANIONIC SURFACTANT | L'OREAL (FR) | 2002-05-07 | — | — | US | disclosed |
| US-5443596-A | Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers | L'OREAL (FR) | 1995-08-22 | — | — | US | disclosed |