Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838626 | 0.90 | MAPT (0.36) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL3860929 | 0.79 | MAPT (0.41) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL28447576 | 0.78 | MAPT (0.35) | MAPTRAB9AMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3857260 | 0.77 | MAPT (0.40) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL25560558 | 0.77 | TLR8 (0.45) | MAPTRAB9ATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL484007 | 0.76 | MAPT (0.33) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL11693804 | 0.74 | CA2 (0.41) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL6671578 | 0.73 | FYN (0.52) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL459453 | 0.73 | FYN (0.52) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL21379734 | 0.72 | ALDH1A1 (0.44) | MAPTMEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992633-B2 | Disulfide dyes | BASF SE (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20140157529-A1 | DISULFIDE DYES | BASF SE (DE) | 2014-06-12 | — | — | US | disclosed |
| US-20080295260-A1 | Disulfide Dyes, Composition Comprising them and Method of Dyeing Hair | CIBA SPECIALTY CHEMICALS CORP. | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080295260-A1 | Disulfide Dyes, Composition Comprising them and Method of Dyeing Hair | STS, CYP2S1, SQOR | MAPT 4591/4885RAB9A 4241/4885MEN1 2919/4885 |
| US-20140157529-A1 | DISULFIDE DYES | KRT18, COL1A1, SULT1A1 | MAPT 1432/4885RAB9A 3890/4885MEN1 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.