Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 3/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114833 | 0.92 | MAOB (0.46) | MAOBMAOAMAP4K4DHFRPFKFB3 | |
| SCHEMBL4102014 | 0.90 | MAOB (0.44) | MAOBMAOAALOX5APFEN1DHFR | |
| SCHEMBL4104502 | 0.80 | MAOB (0.41) | MAOBMAOADHFR | |
| SCHEMBL4097650 | 0.80 | MAOB (0.46) | MAOBMAOAMAP4K4DHFRPFKFB3 | |
| SCHEMBL4113326 | 0.78 | MAP4K4 (0.56) | MAP4K4DHFR | |
| SCHEMBL4096455 | 0.77 | MAOB (0.49) | MAOBMAOAMAP4K4PFKFB3 | |
| SCHEMBL4108022 | 0.77 | MAOB (0.44) | MAOBMAOAALOX5APFEN1DHFR | |
| SCHEMBL4113347 | 0.76 | MAOB (0.45) | MAOBMAOAALOX5APFEN1 | |
| SCHEMBL4107331 | 0.76 | TLR4 (0.47) | DHFR | |
| SCHEMBL4097587 | 0.75 | CTSS (0.51) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009076-A2 | SUBSTITUTED PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | claimed |