SCHEMBL484032

SCHEMBL484032

CC(CN=C=O)c1cccc(C(C)CN=C=O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.40
HDAC4 P56524 3/20 0.39
HDAC8 Q9BY41 3/20 0.39
HDAC2 Q92769 2/20 0.39
CYP3A4 P08684 2/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MDM4 O15151 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
TYR P14679 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CA5A P35218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10537775 0.88 MIF (0.40) MIF
SCHEMBL9179795 0.87 CYP3A4 (0.37) MIFHDAC4HDAC8HDAC2CYP3A4
SCHEMBL462795 0.86 TAAR1 (0.47) MIFCYP3A4TAAR1ALDH1A1HPGD
SCHEMBL29022653 0.86 TAAR1 (0.47) MIFCYP3A4TAAR1ALDH1A1HPGD
SCHEMBL1705584 0.84 MIF (0.53) MIFCYP3A4TAAR1ALDH1A1FFAR1
SCHEMBL2860264 0.83 GBA1 (0.43) MIFHDAC4HDAC8HDAC2CYP3A4
SCHEMBL4799419 0.76 TSHR (0.36) MIFCYP3A4GABRA1GABRB2TAAR1
SCHEMBL6066034 0.76 C3AR1 (0.47) MIFHDAC4CYP3A4SMN1; SMN2TDP1
SCHEMBL21175579 0.76 MIF (0.35) MIF
SCHEMBL9181988 0.74 CYP3A4 (0.46) MIFCYP3A4GABRA1GABRB2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117431008-B Water-based polyurethane coating and preparation method thereof 肇庆华欣特化工涂料有限公司 2024-09-27 CN claimed
CN-117431008-A Water-based polyurethane coating and preparation method thereof 肇庆华欣特化工涂料有限公司 2024-01-23 CN claimed
CN-114927696-A Positive electrode slurry with high cohesiveness and preparation method and application thereof 南通赛得能源有限公司 2022-08-19 CN claimed
US-20220186037-A1 COATED PARTICLES FOR TURF INFILL PREFERRED TECHNOLOGY, LLC 2022-06-16 US claimed
US-9382469-B2 Process for the production of coated proppants ASHLAND-SUDCHEMIE-KERNFEST GMBH (DE) 2016-07-05 US claimed
US-20140345864-A1 METHOD FOR PRODUCING COATED PROPPANTS ASHLAND-SUDCHEMIE-KERNFEST GMBH (DE) 2014-11-27 US claimed
US-20140060833-A1 PROCESS FOR THE PRODUCTION OF COATED PROPPANTS Ashland-Sudchemie-Kemfest GmbH (DE) 2014-03-06 US claimed
WO-2013166198-A1 ANTIMICROBIAL POLYURETHANE MATERIALS AND METHODS OF FORMING AND USING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-11-07 WO claimed
EP-2640804-A1 PROCESS FOR THE PRODUCTION OF COATED PROPPANTS Ashland-Südchemie-Kernfest GmbH (DE) 2013-09-25 EP claimed
EP-2385075-B1 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG IND OHIO INC (US) 2013-08-28 EP claimed
EP-1071539-A1 ABRASIVE ARTICLE WITH TIE COAT AND METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2001-01-31 EP claimed
WO-1999052676-A1 ABRASIVE ARTICLE WITH TIE COAT AND METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-10-21 WO claimed
EP-0794974-A1 STABILIZED POLYESTER SHAPING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1997-09-17 EP claimed
EP-0794978-A1 IMPACT-RESISTANT THERMOPLASTIC SHAPING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1997-09-17 EP claimed
EP-0628541-B1 Carbodiimides and/or oligomeric polycarbodiimides based on 1,3-bis-(1-methyl-1-isocyanatoethyl)-benzene, process for their preparation and their use as stabilizer against hydrolysis BASF AG (DE) 1997-04-16 EP claimed
WO-1996017018-A1 IMPACT-RESISTANT THERMOPLASTIC SHAPING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1996-06-06 WO claimed
US-5498747-A Carbodiimides and/or oligomeric polycarbodiimides based on 1,3-bis (1-methyl-1-isocyanatoethyl)benzene, their preparation, and their use as hydrolysis stabilizers BASF AKTIENGESELLSCHAFT (DE) 1996-03-12 US claimed
EP-0628541-A1 Carbodiimides and/or oligomeric polycarbodiimides based on 1,3-bis-(1-methyl-1-isocyanatoethyl)-benzene, process for their preparation and their use as stabilizer against hydrolysis BASF Aktiengesellschaft (DE) 1994-12-14 EP claimed
US-5218073-A POLYHYDROXY URETHANES FORMED BY REACTION OF REDUCED SUGARS AND ORGANIC DIISOCYANATES E. I. DU PONT DE NEMOURS AND COMPAANY (US) 1993-06-08 US claimed
WO-1992007016-A1 POLYHYDROXY URETHANES FORMED BY REACTION OF REDUCED SUGARS AND ORGANIC DIISOCYANATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-30 WO claimed