Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.51 |
| ▸ | EDNRA | P25101 | 5/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015312 | 0.86 | SCN9A (0.55) | SCN9A | |
| SCHEMBL281339 | 0.83 | SCN9A (0.51) | SCN9A | |
| SCHEMBL281985 | 0.80 | SCN9A (0.62) | SCN9A | |
| SCHEMBL280703 | 0.80 | SCN9A (0.66) | SCN9A | |
| SCHEMBL280904 | 0.80 | SCN9A (0.63) | SCN9A | |
| SCHEMBL281190 | 0.79 | SCN9A (0.66) | SCN9A | |
| SCHEMBL280696 | 0.77 | SCN9A (0.61) | SCN9A | |
| SCHEMBL281214 | 0.76 | SCN9A (0.74) | SCN9A | |
| SCHEMBL280730 | 0.76 | SCN9A (0.66) | SCN9A | |
| SCHEMBL281428 | 0.76 | SCN9A (0.66) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888595-B1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2012-02-01 | — | — | EP | claimed |