Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837965 | 0.95 | ADRB3 (0.41) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4832542 | 0.94 | ADRB3 (0.40) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4894375 | 0.89 | ADRB3 (0.41) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4837960 | 0.88 | ADRB3 (0.42) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4892955 | 0.86 | ADRB3 (0.41) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| Trifluoroacetic Acid SCHEMBL4830634 | 0.85 | ADRB3 (0.40) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4891893 | 0.85 | ADRB3 (0.42) | ADRB3ADRB2ADRB1HPGDNR1I2 | |
| SCHEMBL4830639 | 0.84 | ADRB3 (0.36) | ADRB3HPGDNR1I2ALDH1A1PKM | |
| SCHEMBL4828479 | 0.84 | ADRB3 (0.35) | ADRB3HPGDNR1I2MEN1ALDH1A1 | |
| SCHEMBL5313619 | 0.84 | ADRB3 (0.43) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945304-A2 | IMIDAZO-PYRIDINE CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007048843-A2 | IMIDAZO-PYRIDINE CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |