SCHEMBL484125

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2163659	0.87	APP (0.39)	APPRAD51NPC1RAB9ATOP2A
	SCHEMBL484285	0.85	RAD51 (0.40)	APPRAD51NPC1RAB9AADORA2A
	SCHEMBL2163112	0.85	APP (0.37)	APPRAD51TOP2A
	SCHEMBL2162661	0.85	APP (0.37)	APPRAD51TOP2AMAPTPKM
	SCHEMBL12402982	0.84	APP (0.41)	APPNPC1RAB9AMAPTHRH3
	SCHEMBL12323589	0.82	ALDH1A1 (0.40)	APPRAD51NPC1RAB9AMAPT
	SCHEMBL2163599	0.82	APP (0.39)	APPMAPTTP53ALDH1A1MEN1
	SCHEMBL12323637	0.82	TOP2A (0.37)	APPRAD51NPC1RAB9ATOP2A
	SCHEMBL12403622	0.81	TP53 (0.40)	APPNPC1RAB9AADORA2AMAPT
	SCHEMBL12402841	0.81	RAD51 (0.40)	RAD51NPC1RAB9AADORA2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.