Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.65 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712708 | 0.92 | HDAC6 (0.56) | CCR2 | |
| Hydrochloric Acid SCHEMBL11715522 | 0.91 | HDAC6 (0.55) | CCR2 | |
| SCHEMBL15054310 | 0.85 | SMYD3 (0.54) | CCR2 | |
| SCHEMBL27817430 | 0.82 | CCR2 (0.67) | CCR2 | |
| SCHEMBL743956 | 0.82 | CCR2 (0.67) | CCR2 | |
| SCHEMBL1360171 | 0.81 | CCR2 (0.70) | CCR2 | |
| SCHEMBL744023 | 0.81 | CCR2 (0.70) | CCR2 | |
| SCHEMBL744024 | 0.81 | CCR2 (0.70) | CCR2 | |
| SCHEMBL25936926 | 0.81 | POLB (0.59) | CCR2 | |
| Hydrochloric Acid SCHEMBL745581 | 0.81 | CCR2 (0.69) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418951-C | Cycloamine derivative and its use as medicine | TEIJIN KASEI LTD (JP) | 2008-09-17 | — | — | CN | disclosed |
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| CN-1240699-C | Therapeutic or prophylactic agent for chemokine-associated diseases | TEIJIN LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| CN-1660815-A | Cyclic amine derivatives and their use as drugs | TEIJIN LTD (JP) | 2005-08-31 | — | — | CN | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| CN-1496981-A | Cyclic amine derivatives and their use as pharmaceuticals | ������������ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| CN-1384743-A | Remedies or preventives for diseases in association with chemokines | TEIJIN LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |
| CN-1279668-A | Cyclic amine derivatives and their use as pharmaceuticals | TEIJIN LTD (JP) | 2001-01-10 | — | — | CN | disclosed |