Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779693 | 0.84 | S1PR1 (0.41) | S1PR1ALOX5APPTGER4KDM4EALDH1A1 | |
| SCHEMBL28971006 | 0.69 | KDM4E (0.59) | S1PR1PTGER4KDM4EALDH1A1GLA | |
| SCHEMBL20644538 | 0.68 | S1PR1 (0.46) | S1PR1ALOX5APPTGER4KDM4EALDH1A1 | |
| SCHEMBL19863784 | 0.66 | NPSR1 (0.58) | S1PR1KDM4EALDH1A1 | |
| SCHEMBL3049353 | 0.66 | S1PR1 (0.48) | S1PR1ALOX5APPTGER4KDM4EALDH1A1 | |
| SCHEMBL1206744 | 0.65 | S1PR1 (0.41) | S1PR1ALOX5APPTGER4KDM4EALDH1A1 | |
| SCHEMBL23458895 | 0.65 | BRPF1 (0.39) | CYP11B2CYP11B1ACSS2 | |
| SCHEMBL29965268 | 0.65 | BRPF1 (0.39) | CYP11B2CYP11B1ACSS2 | |
| SCHEMBL13077881 | 0.65 | TSHR (0.61) | S1PR1ALOX5AP | |
| SCHEMBL3061472 | 0.64 | ALOX5AP (0.43) | S1PR1ALOX5APPTGER4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008012623-A1 | BENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |