Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045139 | 0.91 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL28209901 | 0.90 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL26081601 | 0.86 | PPID (0.47) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL6518733 | 0.86 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL9355135 | 0.85 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL6521008 | 0.85 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL6519457 | 0.85 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL6523916 | 0.85 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL698394 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL1557559 | 0.84 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242618-B1 | Transparent optical article and process for preparing same | NIPPON OILS & FATS CO LTD (JP) | 1994-11-02 | — | — | EP | claimed |
| EP-0242618-A2 | Transparent optical article and process for preparing same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-10-28 | — | — | EP | claimed |
| US-7452875-B2 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-11-18 | — | — | US | disclosed |
| US-7427611-B2 | Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-09-23 | — | — | US | disclosed |
| US-7410962-B2 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-08-12 | — | — | US | disclosed |
| US-20080085889-A1 | Amidomethyl-Substituted 1-(Carboxyalkyl) Cyclopentyl-Carbonylamino-Benzazepine-N-Acetic Acid Compounds, Process and Intermediate Products for Their Preparation and Pharmaceutical Compositions Containing Them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-04-10 | — | — | US | disclosed |
| US-20070265244-A1 | AMIDOMETHYL-SUBSTITUTED 1-(CARBOXYALKYL) CYCLOPENTYL-CARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID COMPOUNDS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| US-7262184-B2 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20060281732-A1 | Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAL PHARMACEUTICALS GMBH (DE) | 2006-12-14 | — | — | US | disclosed |
| EP-1670814-A1 | AMIDOMETHYL SUBSTITUTED 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Solvay Pharmaceuticals GmbH (DE) | 2006-06-21 | — | — | EP | disclosed |
| US-20050119247-A1 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-06-02 | — | — | US | disclosed |
| WO-2005030795-A1 | AMIDOMETHYL SUBSTITUTED 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-04-07 | — | — | WO | disclosed |
| EP-0242618-B1 | Transparent optical article and process for preparing same | NIPPON OILS & FATS CO LTD (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-4948854-A | COPOLYMER INCLUDING ITACONIC ACID DIESTER | SEIKO EPSON CORPORATION (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0242618-A2 | Transparent optical article and process for preparing same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281732-A1 | Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | ECE1, MME, ANPEP | ALDH1A1 368/4885L3MBTL1 1996/4885MAPK1 2746/4885 |
| US-20070265244-A1 | AMIDOMETHYL-SUBSTITUTED 1-(CARBOXYALKYL) CYCLOPENTYL-CARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID COMPOUNDS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ECE1, MME, ANPEP | ALDH1A1 394/4885L3MBTL1 2039/4885MAPK1 2672/4885 |
| US-20050119247-A1 | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them | ECE1, MME, ANPEP | ALDH1A1 333/4885L3MBTL1 1978/4885MAPK1 2330/4885 |
| US-20080085889-A1 | Amidomethyl-Substituted 1-(Carboxyalkyl) Cyclopentyl-Carbonylamino-Benzazepine-N-Acetic Acid Compounds, Process and Intermediate Products for Their Preparation and Pharmaceutical Compositions Containing Them | ECE1, MME, ANPEP | ALDH1A1 394/4885L3MBTL1 2039/4885MAPK1 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.