SCHEMBL4843718

SCHEMBL4843718

C=CCN(CC(=O)O)Cc1cccc(OCCc2nc(-c3ccccc3)oc2C)c1

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.83
PPARA Q07869 19/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4854188 0.93 PPARG (0.72) PPARGPPARA
SCHEMBL4854260 0.92 PPARG (0.70) PPARGPPARA
SCHEMBL13718226 0.91 PPARG (1.00) PPARGPPARA
SCHEMBL4846734 0.90 PPARG (0.82) PPARGPPARA
SCHEMBL4848994 0.90 PPARG (0.67) PPARGPPARA
SCHEMBL4852323 0.89 PPARG (0.67) PPARGPPARA
SCHEMBL13717465 0.89 PPARG (1.00) PPARGPPARA
SCHEMBL6624241 0.89 PPARG (0.66) PPARGPPARA
SCHEMBL6622864 0.89 PPARG (0.66) PPARGPPARA
SCHEMBL4852327 0.88 PPARG (0.65) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040254370-A1 Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2004-12-16 US claimed
EP-1445256-A1 CARBOXYLIC ACID DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-08-11 EP claimed
US-7323456-B2 Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-01-29 US disclosed
US-7323456-B2 Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-01-29 US disclosed
US-7323456-B2 Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-01-29 US disclosed
US-20040254370-A1 Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2004-12-16 US disclosed
EP-1445256-A1 CARBOXYLIC ACID DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254370-A1 Carboxylic acid derivatives compounds and agents comprising the compounds as active ingredient SREBF1, GPR119, PPARG PPARG 3/4885PPARA 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.