Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068564 | 1.00 | GHSR (0.53) | GHSR | |
| SCHEMBL3067301 | 0.92 | GHSR (0.53) | GHSR | |
| SCHEMBL3072627 | 0.89 | GHSR (0.57) | GHSR | |
| SCHEMBL3081136 | 0.88 | GHSR (0.52) | GHSR | |
| SCHEMBL3069855 | 0.87 | GHSR (0.52) | GHSR | |
| SCHEMBL3068566 | 0.87 | GHSR (0.45) | GHSR | |
| SCHEMBL3069232 | 0.86 | GHSR (0.53) | GHSR | |
| SCHEMBL3068013 | 0.86 | GHSR (0.55) | GHSR | |
| SCHEMBL13139355 | 0.86 | GHSR (0.52) | GHSR | |
| SCHEMBL3066584 | 0.85 | GHSR (0.57) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951675-A1 | TETRAHYDROISOQUINOLINE AS LXR MODULATORS | Brystol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007047991-A1 | TETRAHYDROISOQUINOLINE AS LXR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-26 | — | — | WO | disclosed |