SCHEMBL4844930

SCHEMBL4844930

CC(=S)CCCCCCCCCCCCCc1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES1 P23141 11/20 0.46
FAAH O00519 9/20 0.43
CCR1 P32246 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43
NCEH1 Q6PIU2 1/20 0.43
DAGLA Q9Y4D2 1/20 0.43
FAAH2 Q6GMR7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4851185 1.00 CES1 (0.46) CES1FAAHCCR1CCR5CCR8
SCHEMBL9680002 0.81 CCR1 (0.49) CES1FAAHCCR1CCR5CCR8
SCHEMBL7949955 0.80 CCR1 (0.50) CES1FAAHCCR1CCR5CCR8
SCHEMBL4849559 0.79 CCR1 (0.49) CES1FAAHCCR1CCR5CCR8
SCHEMBL4849761 0.79 CCR1 (0.49) CES1FAAHCCR1CCR5CCR8
SCHEMBL12131376 0.78 CCR1 (0.51) CES1CCR1CCR5CCR8
SCHEMBL9756771 0.77 HRH1 (0.51) CES1CCR1CCR5CCR8
SCHEMBL7951004 0.77 CCR1 (0.50) CES1FAAHCCR1CCR5CCR8
SCHEMBL7911551 0.76 SMN1; SMN2 (0.53) CES1FAAHCCR1CCR5CCR8
SCHEMBL21929413 0.73 CCR1 (0.49) CES1FAAHCCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7420058-B2 Compound for molecular electronic device having thiol anchoring group, method of synthesizing the compound, and molecular electronic device having molecular active layer obtained from the compound ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2008-09-02 US disclosed
US-20070120121-A1 Compound for molecular electronic device having thiol anchoring group, method of synthesizing the compound, and molecular electronic device having molecular active layer obtained from the compound ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE 2007-05-31 US disclosed