Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.51 |
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | CCR8 | P51685 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951004 | 0.84 | CCR1 (0.50) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL7949955 | 0.84 | CCR1 (0.50) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL4849559 | 0.83 | CCR1 (0.49) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL9680002 | 0.83 | CCR1 (0.49) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL4849761 | 0.83 | CCR1 (0.49) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL12131376 | 0.82 | CCR1 (0.51) | CCR1CCR5CCR8KDM4ELMNA | |
| Dipyridyl SCHEMBL1923113 | 0.80 | CCR1 (0.46) | HRH1CCR1CCR5CCR8KDM4E | |
| Dipyridyl SCHEMBL1318097 | 0.80 | CCR1 (0.46) | HRH1CCR1CCR5CCR8KDM4E | |
| SCHEMBL7949918 | 0.79 | CCR1 (0.49) | CCR1CCR5CCR8KDM4ELMNA | |
| Dipyridyl SCHEMBL701722 | 0.79 | CCR1 (0.45) | HRH1CCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019730-A1 | RNA HYDROLYSIS/CLEAVAGE | MONSANTO COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |