Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045535 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNARAB9ACRHBP | |
| SCHEMBL3535919 | 0.70 | ALDH1A1 (0.53) | ALDH1A1TDP1HPRT1LMNAPOLB | |
| SCHEMBL3459005 | 0.70 | TDP1 (0.38) | ALDH1A1TDP1POLBMAPK1KMT2A | |
| SCHEMBL6047843 | 0.69 | ALDH1A1 (0.47) | ALDH1A1TDP1HPRT1LMNAPOLB | |
| SCHEMBL6950450 | 0.68 | CYP2A6 (0.43) | ALDH1A1PTGS2MAPK1CYP2A6CYP2B6 | |
| SCHEMBL10406683 | 0.68 | CYP2A6 (0.47) | ALDH1A1PTGS2MAPK1CYP2A6CYP2B6 | |
| SCHEMBL7834701 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TDP1HPRT1LMNAPOLB | |
| SCHEMBL27556871 | 0.68 | HPRT1 (0.47) | ALDH1A1TDP1HPRT1LMNAPOLB | |
| SCHEMBL9216438 | 0.68 | MAPT (0.41) | ALDH1A1TDP1LMNARAB9ACRHBP | |
| SCHEMBL29236231 | 0.67 | ALDH1A1 (0.59) | ALDH1A1TDP1HPRT1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323458-B1 | Dihydrobenzodiazepins and their use for treating dyslipidemia | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-29 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |