Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21465893 | 1.00 | TRPA1 (0.50) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL18516822 | 0.84 | MAPT (0.43) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL16004820 | 0.83 | TRPA1 (0.52) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL18878721 | 0.83 | TRPA1 (0.41) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL23030029 | 0.82 | MAPT (0.47) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL319274 | 0.82 | RCE1 (0.46) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL7516031 | 0.82 | RCE1 (0.46) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL20917410 | 0.81 | TRPA1 (0.55) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL20917411 | 0.81 | TRPA1 (0.55) | TRPA1MAPTRCE1HTTALDH1A1 | |
| SCHEMBL31080622 | 0.81 | TRPA1 (0.55) | TRPA1MAPTRCE1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432087-B2 | Method for preparing (2S, 3R, 4S)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2008-10-07 | — | — | US | disclosed |
| US-20050079587-A1 | Method for preparing (2S, 3R, 4S) -4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE | 2005-04-14 | — | — | US | disclosed |
| US-20030219880-A1 | Method for preparing (2s,3r,4s)-4-hydroxyisoleucine and analogues thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-11-27 | — | — | US | disclosed |