Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849397 | 0.90 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2GPBAR1HCRTR1HCRTR2 | |
| SCHEMBL4851712 | 0.89 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL14021727 | 0.88 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6089926 | 0.81 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL14045430 | 0.80 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1HCRTR1HCRTR2 | |
| SCHEMBL4846959 | 0.80 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1HCRTR1HCRTR2 | |
| SCHEMBL4848359 | 0.80 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4850064 | 0.79 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4841446 | 0.78 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL14021745 | 0.78 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-6635655-B1 | Agonists or antagonists of peroxisome proliferator-activated receptors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-10-21 | — | — | US | disclosed |