SCHEMBL4846833

SCHEMBL4846833

Nc1ccc(C(F)(F)F)cc1C(=O)NCC(=O)NCC1CCN(Cc2ccc(Br)cc2)CC1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4848457 0.92 CCR2 (1.00) CCR2
SCHEMBL4842817 0.87 CCR2 (0.66) CCR2
SCHEMBL4841277 0.85 CCR2 (0.76) CCR2
SCHEMBL6205584 0.85 CCR2 (0.63) CCR2
SCHEMBL4844890 0.85 CCR2 (0.84) CCR2
SCHEMBL27580117 0.83 CCR2 (0.68) CCR2
SCHEMBL6209509 0.82 CCR2 (0.71) CCR2
SCHEMBL6205964 0.81 CCR2 (0.81) CCR2
SCHEMBL27520085 0.80 CCR2 (0.67) CCR2
SCHEMBL6205769 0.79 CCR2 (0.77) CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7390830-B1 Remedies or prophylactics for diseases in association with chemokines TEIJIN LIMITED (JP) 2008-06-24 US disclosed
EP-1179341-B1 REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES TEIJIN LTD (JP) 2005-11-09 EP disclosed
CN-1384743-A Remedies or preventives for diseases in association with chemokines TEIJIN LTD (JP) 2002-12-11 CN disclosed
EP-1179341-A1 REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES TEIJIN LIMITED (JP) 2002-02-13 EP disclosed