Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850834 | 0.91 | GAA (0.42) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11581162 | 0.89 | MAPT (0.48) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15402937 | 0.84 | KMT2A (0.66) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11581459 | 0.83 | MAPT (0.50) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6180706 | 0.81 | KMT2A (0.67) | KMT2ALMNANR1I2AHR | |
| SCHEMBL4856408 | 0.80 | KMT2A (0.61) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20814432 | 0.78 | LMNA (0.62) | MAPTKMT2ALMNAGAANR1I2 | |
| SCHEMBL3414696 | 0.77 | KMT2A (0.57) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20814429 | 0.76 | KMT2A (0.54) | CYP1A2CYP2C19KMT2ALMNAMEN1 | |
| SCHEMBL11785501 | 0.76 | CYP1A2 (0.55) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |