SCHEMBL4848046

SCHEMBL4848046

Cn1cc(OC(=O)Nc2ccc(F)cc2-c2ccccc2F)c(C(F)(F)F)n1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 10/20 0.48
LMNA P02545 2/20 0.40
NR3C1 P04150 1/20 0.40
PGR P06401 1/20 0.40
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 3/20 0.38
MAPT P10636 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3041242 0.92 CHRM3 (0.40) CHRM3LMNANR3C1PGRRAB9A
SCHEMBL3024592 0.91 CHRM3 (0.44) CHRM3LMNAGAARAB9ANPSR1
SCHEMBL3043533 0.90 CHRM3 (0.48) CHRM3LMNANR3C1PGRKDM4E
SCHEMBL4835285 0.87 LMNA (0.39) CHRM3LMNANR3C1PGRCHRM2
SCHEMBL1039851 0.85 CHRM3 (0.43) CHRM3LMNANR3C1PGRRAB9A
SCHEMBL3045842 0.84 CHRM3 (0.48) CHRM3
SCHEMBL3034363 0.84 CHRM3 (0.47) CHRM3RAB9A
SCHEMBL4563652 0.84 CHRM3 (0.46) CHRM3LMNAGAARAB9ANPSR1
SCHEMBL1128031 0.83 CHRM3 (0.40) CHRM3CHRM2CHRM1RAB9A
SCHEMBL3035362 0.83 CHRM3 (0.46) CHRM3CHRM2CHRM1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1898704-A1 FUNGICIDAL MIXTURES BASED ON 2,5-DISUBSTITUTED PYRAZOL CARBOXYLIC ACID BIPHENYLAMIDES BASF SE (DE) 2008-03-19 EP disclosed
WO-2007003540-A1 FUNGICIDAL MIXTURES BASED ON 2,5-DISUBSTITUTED PYRAZOL CARBOXYLIC ACID BIPHENYLAMIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 WO disclosed