Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31012425 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL304550 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL304549 | 0.78 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL15470518 | 0.76 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL22827822 | 0.75 | STK17B (0.59) | TDP1MAPK1MEN1KMT2AMAOA | |
| SCHEMBL19244126 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL2606686 | 0.74 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL22799287 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL11215773 | 0.74 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDL3MBTL1TDP1 | |
| SCHEMBL13062771 | 0.74 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2167216-A | — | — | None | — | — | JP | disclosed |
| US-20080146576-A1 | N-(1-Phthalazin-1-ylpiperidin-4-yl)amides as EP2 receptor modulators | BAYER SCHERING PHARMA AG (DE) | 2008-06-19 | — | — | US | disclosed |
| WO-2008028689-A1 | N-(1-PHTHALAZIN-1-YLPIPERIDIN-4-YL)AMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |
| JP-2006151842-A | METHOD FOR PRODUCING OPTICALLY ACTIVE ALKYLPHTHALIDE COMPOUND | TAKASAGO INTERNATL CORP | 2006-06-15 | — | — | JP | disclosed |
| JP-H02167216-A | BATHING AGENT | KAO CORP | 1990-06-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146576-A1 | N-(1-Phthalazin-1-ylpiperidin-4-yl)amides as EP2 receptor modulators | PTGER2, PTGER1, PTGDR2 | KDM4E 2500/4885ALDH1A1 1023/4885HPGD 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.