SCHEMBL4849233

SCHEMBL4849233

C=CC(=O)NCCOCCOC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.46
ZDHHC2 Q9UIJ5 1/20 0.46
TSHR P16473 4/20 0.43
ALDH1A1 P00352 4/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
GLA P06280 2/20 0.38
HPGD P15428 1/20 0.38
TGM2 P21980 2/20 0.35
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PYGL P06737 1/20 0.35
EPHX2 P34913 2/20 0.35
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29519145 1.00 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL29519271 1.00 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL29519122 1.00 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL17107298 1.00 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL29519312 1.00 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL7528699 1.00 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL12328384 0.90 TSHR (0.52) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL12213321 0.90 TSHR (0.52) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL4361183 0.90 TSHR (0.52) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL12328966 0.90 TSHR (0.52) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7329694-B2 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-02-12 US claimed
WO-2024112744-A1 CATALYSTS AND METHODS OF USE THEREOF YALE UNIVERSITY (US) 2024-05-30 WO disclosed
CN-112638519-B stationary phase for chromatography 株式会社大赛璐 2023-11-10 CN disclosed
US-20210252479-A1 STATIONARY PHASE FOR CHROMATOGRAPHY DAICEL CORPORATION (JP) 2021-08-19 US disclosed
EP-3845307-A1 STATIONARY PHASE FOR CHROMATOGRAPHY Daicel Corporation (JP) 2021-07-07 EP disclosed
CN-112638519-A Stationary phase for chromatography 株式会社大赛璐 2021-04-09 CN disclosed
WO-2020045648-A1 STATIONARY PHASE FOR CHROMATOGRAPHY 株式会社ダイセル 2020-03-05 WO disclosed
US-7329694-B2 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-02-12 US disclosed
EP-1445641-B1 OCULAR LENS JOHNSON & JOHNSON VISION CARE (US) 2007-10-03 EP disclosed
US-20040201820-A1 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. 2004-10-14 US disclosed
EP-1445641-A1 OCULAR LENS Johnson & Johnson Vision Care, Inc. (US) 2004-08-11 EP disclosed