SCHEMBL4849451

SCHEMBL4849451

CCCCCc1ccccc1OB(O)O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.59
ALOX5 P09917 1/20 0.53
PTGS2 P35354 1/20 0.53
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52
PPARA Q07869 3/20 0.47
PPARG P37231 2/20 0.44
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4859267 0.98 LIPG (0.62) LIPGALOX5PTGS2THRATHRB
SCHEMBL4859387 0.98 LIPG (0.62) LIPGALOX5PTGS2THRATHRB
SCHEMBL4857505 0.98 LIPG (0.62) LIPGALOX5PTGS2THRATHRB
SCHEMBL4859494 0.98 LIPG (0.62) LIPGALOX5PTGS2THRATHRB
SCHEMBL4858367 0.98 LIPG (0.62) LIPGALOX5PTGS2THRATHRB
SCHEMBL716479 0.98 LIPG (0.62) LIPGALOX5PTGS2THRATHRB
SCHEMBL3968465 0.95 LIPG (0.51) LIPGALOX5PTGS2THRATHRB
SCHEMBL29102724 0.91 LIPG (0.50) LIPGALOX5PTGS2THRATHRB
SCHEMBL28506217 0.88 BID (0.47) LIPGALOX5PTGS2THRATHRB
SCHEMBL4860135 0.87 LIPG (0.42) LIPGALOX5PTGS2THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410925-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-08-12 US disclosed
US-7008897-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US disclosed
US-20060030480-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2006-02-09 US disclosed
US-20040209763-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed