Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL553153 | 0.91 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1EPHX2THRB | |
| SCHEMBL18016179 | 0.87 | MEN1 (0.50) | KMT2AMEN1ALDH1A1EPHX2THRB | |
| SCHEMBL13862904 | 0.87 | MEN1 (0.50) | KMT2AMEN1ALDH1A1EPHX2THRB | |
| SCHEMBL12036308 | 0.85 | MEN1 (0.47) | KMT2AMEN1ALDH1A1EPHX2THRB | |
| SCHEMBL1197607 | 0.84 | ALDH1A1 (0.65) | KMT2AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL23841879 | 0.84 | MEN1 (0.53) | KMT2AMEN1ALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL24811381 | 0.84 | MEN1 (0.53) | KMT2AMEN1ALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL23175576 | 0.84 | MEN1 (0.53) | KMT2AMEN1ALDH1A1EPHX2SMN1; SMN2 | |
| SCHEMBL2608239 | 0.83 | ALDH1A1 (0.58) | KMT2AALDH1A1EPHX2SMN1; SMN2LMNA | |
| SCHEMBL2608244 | 0.81 | ALDH1A1 (0.57) | KMT2AALDH1A1EPHX2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | claimed |
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-20040201820-A1 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-14 | — | — | US | disclosed |
| EP-1445641-A1 | OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |