⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400577 | 0.84 | — | — | |
| SCHEMBL11970800 | 0.81 | — | — | |
| SCHEMBL8972924 | 0.79 | — | — | |
| SCHEMBL15403780 | 0.76 | — | — | |
| SCHEMBL9147130 | 0.74 | — | — | |
| SCHEMBL1148057 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL3794481 | 0.71 | DDB1 (0.30) | — | |
| SCHEMBL211168 | 0.71 | DDB1 (0.30) | — | |
| SCHEMBL8972514 | 0.71 | CHRM2 (0.33) | — | |
| SCHEMBL28297520 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396953-B2 | Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-07-08 | — | — | US | disclosed |
| US-20070167519-A1 | Novel Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-07-19 | — | — | US | disclosed |
| EP-1763500-A1 | NOVEL ANGIOGENESIS INHIBITORS AND PHARMACEUTICAL AND COSMETIC USE THEREOF | Galderma Research & Development, S.N.C. (FR) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006010859-A1 | NOVEL ANGIOGENESIS INHIBITORS AND PHARMACEUTICAL AND COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-02-02 | — | — | WO | disclosed |