SCHEMBL4850434

SCHEMBL4850434

CC(S)SCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC6A4 P31645 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 3/20 0.41
SLC6A2 P23975 2/20 0.41
MAOA P21397 1/20 0.41
SLC6A3 Q01959 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CYP2A6 P11509 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10899765 0.81 L3MBTL1 (0.47) PPARGPPARASLC6A4L3MBTL1ATM
SCHEMBL560907 0.81 PPARG (0.45) PPARGPPARASLC6A4L3MBTL1ATM
SCHEMBL9355886 0.79 SLC6A2 (0.45) PPARGPPARASLC6A4L3MBTL1ATM
SCHEMBL21462872 0.78 TP53 (0.41) PPARGPPARAL3MBTL1ATMPOLB
SCHEMBL24013069 0.77 IDO1 (0.43) PPARGPPARASLC6A4L3MBTL1ATM
SCHEMBL10585977 0.77 NPSR1 (0.47) PPARGPPARASLC6A4L3MBTL1ATM
SCHEMBL1467047 0.77 SLC6A2 (0.52) PPARGPPARASLC6A4POLBTAAR1
SCHEMBL7215558 0.77 PPARG (0.42) PPARGPPARASLC6A4L3MBTL1ATM
SCHEMBL27690898 0.77 PPARG (0.42) PPARGPPARASLC6A4L3MBTL1ATM
SCHEMBL2878611 0.76 L3MBTL1 (0.42) PPARGPPARASLC6A4L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7338984-B2 Resin composition containing ultrafine inorganic particle MITSUI CHEMICALS, INC. (JP) 2008-03-04 US disclosed
EP-1544220-B1 RESIN COMPOSITION CONTAINING ULTRAFINE INORGANIC PARTICLE MITSUI CHEMICALS INC (JP) 2007-01-10 EP disclosed
US-20050261406-A1 Resin composition containing ultrafine inorganic particle MITSUI CHEMICALS, INC. (JP) 2005-11-24 US disclosed
EP-1544220-A1 RESIN COMPOSITION CONTAINING ULTRAFINE INORGANIC PARTICLE Mitsui Chemicals, Inc. (JP) 2005-06-22 EP disclosed