Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.35 |
| ▸ | FLT1 | P17948 | 5/20 | 0.35 |
| ▸ | FLT4 | P35916 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 4/20 | 0.33 |
| ▸ | LCK | P06239 | 3/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.33 |
| ▸ | TEK | Q02763 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226703 | 0.92 | SMN1; SMN2 (0.39) | KDRSMN1; SMN2NPSR1METLCK | |
| SCHEMBL4242226 | 0.83 | SMN1; SMN2 (0.43) | KDRFLT1FLT4SMN1; SMN2NPSR1 | |
| SCHEMBL4233984 | 0.82 | KDR (0.38) | KDRCCR3 | |
| SCHEMBL4233515 | 0.81 | HTR4 (0.43) | KDRMETLCKHTR4ADRB2 | |
| SCHEMBL4237062 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1MCHR1FGFR1 | |
| SCHEMBL4238135 | 0.78 | SMN1; SMN2 (0.41) | KDRFLT1FLT4SMN1; SMN2NPSR1 | |
| SCHEMBL4888299 | 0.78 | MCHR1 (0.37) | KDRSMN1; SMN2NPSR1CCR3MCHR1 | |
| SCHEMBL4229610 | 0.78 | CCR3 (0.41) | KDRFLT1FLT4SMN1; SMN2NPSR1 | |
| SCHEMBL4229335 | 0.78 | KMT2A (0.37) | KDRMETLCKHTR4ADRB2 | |
| SCHEMBL4686817 | 0.77 | KDR (0.40) | KDRFLT1FLT4SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |