Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.53 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850691 | 1.00 | CCR2 (0.53) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4840720 | 0.89 | CCR2 (0.56) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4840729 | 0.89 | CCR2 (0.56) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4844669 | 0.87 | NPFFR2 (0.56) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4844658 | 0.87 | NPFFR2 (0.56) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4847319 | 0.86 | CCR2 (0.54) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4847317 | 0.86 | CCR2 (0.54) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4848529 | 0.86 | NPFFR2 (0.52) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4848526 | 0.86 | NPFFR2 (0.52) | CCR2NPFFR2KCNH2CACNA1IBCHE | |
| SCHEMBL4848488 | 0.83 | NPFFR2 (0.60) | CCR2NPFFR2KCNH2CACNA1IBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |