Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.38 |
| ▸ | GNRHR | P30968 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593665 | 0.86 | SCN9A (0.40) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL3606824 | 0.86 | SCN9A (0.40) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL282029 | 0.83 | SCN9A (0.47) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL2304043 | 0.81 | CHRM5 (0.58) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL281757 | 0.80 | CHRM5 (0.60) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL3328870 | 0.75 | SCN9A (0.42) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL281593 | 0.75 | CHRM5 (0.60) | CHRM5CA12CA1CA2CA9 | |
| SCHEMBL3329555 | 0.70 | SCN9A (0.46) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL27791607 | 0.69 | SCN9A (0.47) | SCN9ASCN7ASCN5ASCN2ASCN8A | |
| SCHEMBL18606955 | 0.68 | CACNA1G (0.45) | SCN9ASCN7ASCN5ASCN2ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008046083-A2 | USE OF OXINDOLE COMPOUNDS AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2008-04-17 | — | — | WO | disclosed |