SCHEMBL4852015

SCHEMBL4852015

c1ccc2cc3c(ccc4cc5ccc6ccccc6c5cc43)cc2c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.84
HSD17B10 Q99714 3/20 0.84
CYP1B1 Q16678 2/20 0.84
HIF1A Q16665 1/20 0.84
CYP1A2 P05177 3/20 0.65
HPGD P15428 2/20 0.65
CYP2A6 P11509 1/20 0.63
TSHR P16473 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
HPRT1 P00492 3/20 0.57
ERBB2 P04626 1/20 0.52
FYN P06241 1/20 0.52
MAOA P21397 1/20 0.52
ACHE P22303 1/20 0.52
AHR P35869 1/20 0.52
PAX8 Q06710 1/20 0.46
TRPM4 Q8TD43 1/20 0.46
CYP1A1 P04798 1/20 0.45
MAPT P10636 1/20 0.45
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4847337 0.97 ALDH1A1 (0.80) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL30384949 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL29352401 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL29362929 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL28804503 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL4853966 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
Dibenz[A,H]Anthracene SCHEMBL8873918 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL55324 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL4845522 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
Phenanthrene SCHEMBL27665236 0.97 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed