SCHEMBL4852052

SCHEMBL4852052

Nc1ccc(N(c2ccc(N)cc2)c2ccc(-c3ccc(N(c4ccc(N)cc4)c4ccc(N)cc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.67
CYP3A4 P08684 7/20 0.67
TDP1 Q9NUW8 5/20 0.67
MAPT P10636 4/20 0.67
KDM4E B2RXH2 3/20 0.67
L3MBTL1 Q9Y468 2/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2D6 P10635 1/20 0.67
CYP2C9 P11712 1/20 0.67
CYP2C19 P33261 1/20 0.67
TP53 P04637 3/20 0.65
HSD17B10 Q99714 4/20 0.52
TAAR1 Q96RJ0 3/20 0.52
ALOX15 P16050 4/20 0.50
MAPK1 P28482 3/20 0.50
PSMD14 O00487 1/20 0.50
TSHR P16473 1/20 0.50
RECQL P46063 1/20 0.50
GFER P55789 1/20 0.50
MEN1 O00255 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29215915 1.00 ALDH1A1 (0.67) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL308803 0.91 TDP1 (0.78) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL2009254 0.91 TDP1 (0.78) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL69032 0.90 ALDH1A1 (0.86) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL7012980 0.90 ALDH1A1 (0.86) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL3478291 0.90 ALDH1A1 (0.86) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL12714629 0.90 ALDH1A1 (0.86) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL21310502 0.90 ALDH1A1 (0.77) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL13915193 0.90 ALDH1A1 (0.86) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL7793770 0.90 ALDH1A1 (0.86) ALDH1A1CYP3A4TDP1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200377647-A1 RESIN COMPOSITION, RESIN SHEET, CURED RESIN PRODUCT, RESIN SUBSTRATE, AND LAMINATE SUBSTRATE TDK CORPORATION (JP) 2020-12-03 US disclosed
US-20200377647-A1 RESIN COMPOSITION, RESIN SHEET, CURED RESIN PRODUCT, RESIN SUBSTRATE, AND LAMINATE SUBSTRATE TDK CORPORATION (JP) 2020-12-03 US disclosed
US-7378203-B2 Ferrocene(di)carboxaldehyde N-phenylhydrazone and monomeric, bridged or polymeric derivatives; good mechanical and electrostatic properties; can be used with liquid and dry toners to produce high quality images; imaging systems can be maintained after repeated cycling; electrography SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-27 US disclosed
US-20060210897-A1 Charge transport materials having at least a metallocene group S-PRINTING SOLUTION CO., LTD. (KR) 2006-09-21 US disclosed