SCHEMBL4852645

SCHEMBL4852645

c1ccc2c(c1)ccc1ccc3c4ccc5ccc6ccccc6c5c4ccc3c12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.70
ALDH1A1 P00352 4/20 0.70
CYP1A2 P05177 4/20 0.70
HPGD P15428 3/20 0.70
THRB P10828 1/20 0.70
HPRT1 P00492 3/20 0.68
TSHR P16473 4/20 0.58
CYP2A6 P11509 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
CYP3A4 P08684 3/20 0.54
HIF1A Q16665 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPK1 P28482 2/20 0.54
ERBB2 P04626 1/20 0.54
FYN P06241 1/20 0.54
MAOA P21397 1/20 0.54
ACHE P22303 1/20 0.54
AHR P35869 1/20 0.54
CASP1 P29466 1/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31154475 0.97 HPRT1 (0.74) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL30110312 0.97 HPRT1 (0.74) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL4851868 0.97 HPRT1 (0.74) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL4888511 0.97 HSD17B10 (0.67) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL4852074 0.97 HPRT1 (0.74) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL535641 0.97 HPRT1 (0.74) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL4847322 0.97 HSD17B10 (0.65) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL4846677 0.94 HPRT1 (0.78) HSD17B10ALDH1A1CYP1A2HPGDTHRB
SCHEMBL4853390 0.94 HPRT1 (0.78) HSD17B10ALDH1A1CYP1A2HPGDTHRB
Chrysene SCHEMBL18546560 0.92 HSD17B10 (0.75) HSD17B10ALDH1A1CYP1A2HPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052506-B1 AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES FLEXENABLE LTD (GB) 2020-06-03 EP disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed