SCHEMBL535641

SCHEMBL535641

c1ccc2c(c1)ccc1c2ccc2ccc3ccccc3c21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.74
HSD17B10 Q99714 4/20 0.67
ALDH1A1 P00352 4/20 0.67
CYP1A2 P05177 3/20 0.67
HPGD P15428 3/20 0.67
THRB P10828 1/20 0.67
TDP1 Q9NUW8 3/20 0.63
TSHR P16473 2/20 0.63
CYP2A6 P11509 1/20 0.63
ERBB2 P04626 1/20 0.58
FYN P06241 1/20 0.58
MAOA P21397 1/20 0.58
ACHE P22303 1/20 0.58
AHR P35869 1/20 0.58
HIF1A Q16665 3/20 0.52
CYP1B1 Q16678 1/20 0.52
PAX8 Q06710 1/20 0.52
MAPK1 P28482 3/20 0.52
CYP3A4 P08684 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30110312 1.00 HPRT1 (0.74) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL31154475 1.00 HPRT1 (0.74) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL4851868 1.00 HPRT1 (0.74) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL4852074 1.00 HPRT1 (0.74) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL4852645 0.97 HSD17B10 (0.70) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL4846677 0.97 HPRT1 (0.78) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL4853390 0.97 HPRT1 (0.78) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
Chrysene SCHEMBL18546560 0.95 HSD17B10 (0.75) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL4845945 0.95 HSD17B10 (0.75) HPRT1HSD17B10ALDH1A1CYP1A2HPGD
SCHEMBL4888511 0.95 HSD17B10 (0.67) HPRT1HSD17B10ALDH1A1CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240334724-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2024-10-03 US claimed
WO-2023085123-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT キヤノン株式会社 2023-05-19 WO claimed
US-8961830-B2 Electroactive polymers containing pendant pi-interacting/binding substituents, their carbon nanotube composites, and processes to form the same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-02-24 US claimed
EP-2260035-B1 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2014-08-20 EP claimed
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof Crysoptic KK (JP) 2011-06-23 US claimed
EP-2260035-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2010-12-15 EP claimed
US-20100071717-A1 METHOD AND APPARATUS FOR CLEANING VEHICLES R. LEWIS TECHNOLOGIES, INC. (US) 2010-03-25 US claimed
WO-2009109781-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2009-09-11 WO claimed
WO-2006135453-A1 METHOD AND APPARATUS FOR CLEANING VEHICLES R. LEWIS TECHNOLOGIES, INC. (US) 2006-12-21 WO claimed
US-4864033-A ATTACHED TO POLYSILOXANE BACKBONE, FOR CHROMATOGRAPHIC SEPARATION OF POLYCYCLIC AROMATIC HYDROCARBONS BRIGHAM YOUNG UNIVERSITY (US) 1989-09-05 US claimed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-20250270203-A1 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS PHILIP MORRIS PRODUCTS S.A. (CH) 2025-08-28 US disclosed
US-20250268910-A1 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS PHILIP MORRIS PRODUCTS S.A. (CH) 2025-08-28 US disclosed
US-12227625-B2 Composite materials comprising mechanical ligands NANOCORE APS (DK) 2025-02-18 US disclosed
US-20240357923-A1 NITROGENATED AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2024-10-24 US disclosed
US-4613558-A Hydrogenated amorphous silicon photosensitive method for electrophotography CANON KABUSHIKI KAISHA (JP) 1986-09-23 US disclosed
US-4557990-A Hydrogenated amorphous silicon photosensitive member for electrophotography CANON KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed
US-4551405-A Image forming process employing member with a depletion layer CANON KABUSHIKI KAISHA (JP) 1985-11-05 US disclosed
US-4461819-A HYDROGENATED AMORPHOUS SILICON CHARGE GENERATION LAYER CANON KABUSHIKI KAISHA (JP) 1984-07-24 US disclosed
US-3965049-A One-step synthesis of aromatic organic diselenides XEROX CORPORATION (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270203-A1 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS CHRNA7, CHRNA1, CHRNA6 HPRT1 1369/4885HSD17B10 1628/4885ALDH1A1 1029/4885
US-20240357923-A1 NITROGENATED AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME NES, NUCB2, NUTF2 HPRT1 318/4885HSD17B10 3374/4885ALDH1A1 2539/4885
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof CCNB1, CCNB2, CCNE2 HPRT1 878/4885HSD17B10 3435/4885ALDH1A1 3686/4885
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 HPRT1 3652/4885HSD17B10 1170/4885ALDH1A1 3874/4885
US-20250268910-A1 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS CHRNA1, CHRNG, CHRM3 HPRT1 1925/4885HSD17B10 2079/4885ALDH1A1 1163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.