Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.62 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849315 | 0.93 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL12328963 | 0.91 | ZDHHC20 (0.57) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL4846067 | 0.89 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL5432342 | 0.89 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL19141793 | 0.89 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL24715024 | 0.89 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL9889645 | 0.89 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL5530407 | 0.89 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL10053108 | 0.88 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL10932322 | 0.88 | ZDHHC20 (0.71) | ZDHHC20ZDHHC2TSHREPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | claimed |
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-20040201820-A1 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-14 | — | — | US | disclosed |
| EP-1445641-A1 | OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |