SCHEMBL4853451

SCHEMBL4853451

C1=Cc2cc3cc4ccccc4cc3c3cccc1c23

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.41
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41
AHR P35869 1/20 0.41
ALDH1A1 P00352 11/20 0.40
HSD17B10 Q99714 8/20 0.40
HPGD P15428 6/20 0.40
HIF1A Q16665 3/20 0.40
CYP1B1 Q16678 1/20 0.40
THRB P10828 1/20 0.40
TSHR P16473 4/20 0.37
MAPK1 P28482 2/20 0.37
CASP1 P29466 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 3/20 0.34
GAA P10253 2/20 0.34
TP53 P04637 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4855642 0.98 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4846620 0.89 ALDH1A1 (0.57) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4853146 0.87 ALDH1A1 (0.51) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4854491 0.86 CYP1A2 (0.49) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL30879493 0.86 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL25508 0.86 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
Benzene SCHEMBL20788840 0.84 ALDH1A1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4852698 0.84 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL11299904 0.79 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4852035 0.78 ALDH1A1 (0.41) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed