Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4854617 | 0.99 | DRD2 (0.62) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4848665 | 0.93 | DRD2 (0.60) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| SCHEMBL4854957 | 0.93 | DRD2 (0.64) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4855743 | 0.92 | DRD2 (0.63) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| SCHEMBL4856188 | 0.90 | DRD2 (0.66) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4854584 | 0.88 | DRD2 (0.62) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4847552 | 0.87 | DRD2 (0.60) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| SCHEMBL4850046 | 0.87 | DRD2 (0.61) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4856369 | 0.87 | DRD2 (0.59) | DRD2ADRA1ADRD4TMEM97SIGMAR1 | |
| SCHEMBL14003468 | 0.86 | DRD2 (0.60) | DRD2ADRA1AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446204-B2 | Amino substituted aryloxybenzylpiperidine derivatives | H. LUNDBECK A/S (DK) | 2008-11-04 | — | — | US | claimed |