SCHEMBL4853519

SCHEMBL4853519

c1ccc2c(c1)ccc1c2ccc2cc3ccc4cccc5ccc(c21)c3c45

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.81
ERBB2 P04626 1/20 0.81
FYN P06241 1/20 0.81
MAOA P21397 1/20 0.81
ACHE P22303 1/20 0.81
AHR P35869 1/20 0.81
ALDH1A1 P00352 7/20 0.64
HSD17B10 Q99714 7/20 0.64
HPGD P15428 5/20 0.64
THRB P10828 1/20 0.64
HPRT1 P00492 4/20 0.56
TSHR P16473 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP2A6 P11509 1/20 0.48
CYP1B1 Q16678 2/20 0.46
HIF1A Q16665 2/20 0.46
CYP3A4 P08684 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP1A1 P04798 1/20 0.44
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[Def]Chrysene SCHEMBL17008909 0.94 CYP1A2 (0.92) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL27576064 0.94 CYP1A2 (0.77) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL21328003 0.94 CYP1A2 (0.92) CYP1A2ERBB2FYNMAOAACHE
Benzo[Def]Chrysene SCHEMBL5473588 0.92 CYP1A2 (0.96) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4851933 0.92 CYP1A2 (0.73) CYP1A2ERBB2FYNMAOAACHE
Benzo[E]Pyrene SCHEMBL6268603 0.92 CYP1A2 (0.96) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5481478 0.90 CYP1A2 (0.66) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5483808 0.90 CYP1A2 (0.84) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4847355 0.90 CYP1A2 (0.77) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4847418 0.90 CYP1A2 (0.77) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed