Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL8410955 | 1.00 | ALDH1A1 (0.67) | — | |
| Alcohol SCHEMBL10579528 | 0.94 | — | — | |
| Alcohol SCHEMBL207379 | 0.94 | — | — | |
| Alcohol SCHEMBL27479873 | 0.94 | — | — | |
| Alcohol SCHEMBL377734 | 0.94 | TSHR (0.75) | — | |
| Alcohol SCHEMBL27667531 | 0.89 | — | — | |
| Alcohol SCHEMBL9413741 | 0.89 | ALDH1A1 (0.67) | — | |
| Alcohol SCHEMBL27658960 | 0.89 | — | — | |
| Alcohol SCHEMBL28932155 | 0.89 | — | — | |
| Alcohol SCHEMBL28685079 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063192-A | Synthesis method of dopamine hydrochloride | 武汉武药制药有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-1740100-B1 | XANTHENE DYES | BIOSEARCH TECHNOLOGIES INC (US) | 2016-10-12 | — | — | EP | disclosed |
| US-9228225-B2 | Xanthene dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-20080214811-A1 | XANTHENE DYES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| US-7344701-B2 | Xanthene dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| EP-1406946-B1 | POSITIVELY CHARGED AMPHIPHILIC BLOCK COPOLYMER AS DRUG CARRIER AND COMPLEX THEREOF WITH NEGATIVELY CHARGED DRUG | SAMYANG CORP (KR) | 2007-06-20 | — | — | EP | disclosed |
| US-7226616-B2 | Positively charged amphiphilic block copolymer as drug carrier and complex thereof with negatively charged drug | SAMYANG CORPORATION (KR) | 2007-06-05 | — | — | US | disclosed |
| EP-1740100-A1 | XANTHENE DYES | Biosearch Technologies, Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005102176-A1 | XANTHENE DYES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2005-11-03 | — | — | WO | disclosed |
| US-20050170363-A1 | Xanthene dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2005-08-04 | — | — | US | disclosed |
| US-20040234494-A1 | Positively charged amphiphilic block copolymer as drug carrier and complex thereof with negatively charged drug | SAMYANG HOLDINGS CORPORATION (KR) | 2004-11-25 | — | — | US | disclosed |
| CN-1531566-A | Positively charged amphiphilic block copolymers as drug carriers and complexes thereof with negatively charged drugs | ������������ʽ���� | 2004-09-22 | — | — | CN | disclosed |
| EP-1406946-A1 | POSITIVELY CHARGED AMPHIPHILIC BLOCK COPOLYMER AS DRUG CARRIER AND COMPLEX THEREOF WITH NEGATIVELY CHARGED DRUG | Samyang Corporation (KR) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003008480-A1 | POSITIVELY CHARGED AMPHIPHILIC BLOCK COPOLYMER AS DRUG CARRIER AND COMPLEX THEREOF WITH NEGATIVELY CHARGED DRUG | SAMYANG CORPORATION (KR) | 2003-01-30 | — | — | WO | disclosed |
| EP-0842246-A4 | DETERGENT COMPOSITION COMPRISING CATIONIC ESTER SURFACTANT AND PROTEASE ENZYME | PROCTER & GAMBLE (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0842246-A1 | DETERGENT COMPOSITION COMPRISING CATIONIC ESTER SURFACTANT AND PROTEASE ENZYME | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003156-A1 | DETERGENT COMPOSITION COMPRISING CATIONIC ESTER SURFACTANT AND PROTEASE ENZYME | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-30 | — | — | WO | disclosed |
| EP-0688165-A1 | A HERBICIDE PREPARATION, PROCESS FOR PRODUCING IT AND AN ACTIVATING ADDITIVE FOR APPLICATION THEREWITH | KVK AGRO A/S (DK) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994019941-A1 | A HERBICIDE PREPARATION, A PROCESS FOR PRODUCING IT AND AN ACTIVATING ADDITIVE FOR APPLICATION THEREWITH | KVK AGRO A/S (DK) | 1994-09-15 | — | — | WO | disclosed |