SCHEMBL4854148

SCHEMBL4854148

CCN(Cc1ccccc1O)Cc1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.55
MAPT P10636 3/20 0.54
POLB P06746 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 2/20 0.54
ALDH1A1 P00352 2/20 0.54
KMT2A Q03164 2/20 0.54
THRB P10828 1/20 0.54
APEX1 P27695 1/20 0.54
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
RECQL P46063 1/20 0.54
CACNA1B Q00975 1/20 0.54
APBA1 Q02410 1/20 0.54
MCL1 Q07820 1/20 0.54
HKDC1 Q2TB90 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ACHE P22303 1/20 0.53
HTR1A P08908 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31038835 0.96 PRKCI (0.60) PRKCIMAPTPOLBKDM4EMEN1
SCHEMBL1822448 0.96 PRKCI (0.60) PRKCIMAPTPOLBKDM4EMEN1
SCHEMBL20175942 0.92 TSHR (0.59) PRKCIMAPTPOLBKDM4EMEN1
Hydrochloric Acid SCHEMBL10587169 0.92 ACHE (0.59) PRKCIMAPTPOLBKDM4EMEN1
SCHEMBL13051280 0.90 TSHR (0.58) PRKCIMAPTPOLBKDM4EMEN1
SCHEMBL15283002 0.86 HSPA5 (0.59) MAPTPOLBKDM4EMEN1ALDH1A1
SCHEMBL18197359 0.85 TSHR (0.53) PRKCIMAPTPOLBKDM4EMEN1
SCHEMBL26243104 0.85 TSHR (0.49) PRKCIMAPTPOLBKDM4EMEN1
SCHEMBL9388579 0.85 TSHR (0.53) PRKCIMAPTPOLBKDM4EMEN1
SCHEMBL26522270 0.84 AKR1B1 (0.52) PRKCIMAPTPOLBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024054972-A2 RADIONUCLIDE COMPOSITION AND METHOD OF USING SAME FOR DETECTION OF TUMOR CELLS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-03-14 WO disclosed
WO-2023070004-A1 TARGETED RADIOTHERANOSTICS BASED ON POLYAZAMACROCYCLIC, MIXED-DONOR SCAFFOLDS LINKED TO A TARGETING VECTOR THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-04-27 WO disclosed
US-8168743-B2 Curable benzoxazine macromonomers, their preparation and cured products HENKEL AG & CO. KGAA (DE) 2012-05-01 US disclosed
US-20100210787-A1 CURABLE BENZOXAZINE MACROMONOMERS, THEIR PREPARATION AND CURED PRODUCTS HENKEL AG & CO. KGAA (DE) 2010-08-19 US disclosed